Responding to R-spondin: slit2 potentiates intestinal regeneration.
نویسندگان
چکیده
Gastrointestinal toxicity of chemoradiotherapy treatment in late-stage cancer patients limits tolerable doses and effectiveness of treatments. Zhou and colleagues in Nature (Zhou et al., 2013) suggest that activating Robo/Slit signaling in concert with R-Spondin potentiates Wnt signaling in intestinal stem cells and drives successful intestinal regeneration and recovery.
منابع مشابه
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ورودعنوان ژورنال:
- Cell stem cell
دوره 13 5 شماره
صفحات -
تاریخ انتشار 2013